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Hormone therapy

Treatment for cancers driven by hormone signalling.

Some cancers depend on hormone signalling to grow. In those cancers, treatment that reduces or blocks that signalling is an important part of care, often over years rather than months.

What it involves

What hormone therapy involves.

Where it applies

Most commonly in hormone-receptor-positive breast cancer and in prostate cancer, where receptor status is established by pathology.

Receptor testing

Testing on the tumour tissue determines whether hormone-directed treatment is relevant at all.

Duration

Hormone therapy is frequently continued for several years, and adherence over time has a real influence on outcome.

Expected effects

Effects vary by drug and may include hot flushes, joint or muscle symptoms, mood or sleep change, sexual health effects and fatigue.

Bone and metabolic health

Some hormone treatments affect bone density and metabolic parameters, so monitoring and preventive measures may be advised.

Long-term review

Ongoing review addresses tolerability, adherence, symptom management and surveillance alongside the rest of the follow-up plan.

Do not stop or change hormone therapy on your own. Side effects are often manageable, and stopping treatment early can affect outcomes; discuss any difficulty with your treating team.

Review your hormone therapy plan and its side effects.

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