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Therapy A-Z

Treatment approaches, explained in general terms.

The main categories of cancer treatment discussed on this website, with an outline of where each is generally used and what it requires.

8 entries

A

Antibody-drug conjugatesTargeted delivery

Treatments that link an antibody to a cytotoxic payload, so delivery is directed towards cells carrying a particular target.

Target expression is usually assessed on tissue before an ADC is considered. Use requires specialist selection and monitoring, and side effects differ between products.

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C

CAR-T cell therapyCellular therapy

A cellular therapy considered in selected blood cancers, in which a patient's own immune cells are modified in a laboratory.

It is delivered only in specialist centres with intensive monitoring, and suitability is determined solely after detailed specialist assessment. Nothing on this website is a statement of suitability.

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ChemotherapySystemic treatment

Systemic treatment given in cycles, used in curative, adjuvant, neoadjuvant and symptom-directed settings.

Regimen, schedule and supportive medication are clinical decisions. This website does not provide dosing or scheduling information.

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Clinical trial participationResearch participation

Taking part in a research study, discussed only where a study is open, relevant and appropriate for the individual.

A trial review is not the same as eligibility or enrolment: eligibility is assessed by the team running the study, after screening and informed consent.

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H

Hormone therapySystemic treatment

Treatment directed at hormone signalling, considered in receptor-positive breast cancer and in prostate cancer.

It is often given over long periods, and the balance of benefit and side effects is reviewed during follow-up.

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I

ImmunotherapyImmune-directed treatment

Treatment that acts on immune regulation rather than on the cancer cell directly.

Use depends on the cancer type, relevant biomarkers and the individual clinical picture. Immune-related side effects require specific monitoring and management.

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S

Supportive and palliative treatmentSymptom-directed care

Symptom-directed treatment that can be provided alongside active cancer treatment.

It is not limited to end-of-life care, and a referral does not itself mean anticancer treatment is being stopped.

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T

Targeted therapyMolecularly directed treatment

Treatment directed at a specific molecular alteration in the cancer.

It can be considered when a relevant alteration is present, in the appropriate clinical context. The presence of an alteration does not by itself mean a particular treatment will work.

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Related:Molecular testingReport interpretation

The A-Z directories provide general educational information. The relevance of a biomarker, test or therapy depends on the individual diagnosis and clinical context, and should be interpreted with a qualified healthcare professional. Nothing in this index is a treatment recommendation, a dosing instruction or a statement of suitability for any individual. Treatment selection requires specialist assessment.

Understanding the terms is a starting point, not a plan.

A consultation places these findings in the context of an individual clinical situation.

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